2. Signaling Pathways
  3. Epigenetics
  4. Epigenetic Reader Domain
  5. Epigenetic Reader Domain Ligand

Epigenetic Reader Domain Ligand

Epigenetic Reader Domain Ligands (13):

Cat. No. Product Name Effect Purity
  • HY-181496
    (S)-JQ-35-Boc
    		Ligand
    (S)-JQ-35-Boc is a BRD4 ligand. (S)-JQ-35-Boc can be used to synthesize BRD4 degrader RAJQ14 (HY-181495). RAJQ14 can be used for cancer research.
  • HY-181952
    BRD9 ligand-11
    		Ligand
    BRD9 ligand-11 is a BRD9 PROTAC ligand. BRD9 ligand-11 can be conjugated with E3 ligase Ligand (HY-125845) and linker to synthesize PROTAC BRD9 Degrader-11 (HY-181951). PROTAC BRD9 Degrader-11 can be used for cancer research.
  • HY-175242
    PROTAC BRD4 ligand-4
    		Ligand
    PROTAC BRD4 ligand-4 is a BRD4 ligand, which can be used to synthesize PROTAC BRD4 Degrader-37 (HY-175225).
  • HY-176369
    PROTAC BRD4 ligand-1-NH-PEG-phenol-PEG-COOtBu
    		Ligand
    PROTAC BRD4 ligand-1-NH-PEG-phenol-PEG-COOtBu is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for BRD4 and a PROTAC linker. PROTAC BRD4 ligand-1-NH-PEG-phenol-PEG-COOtBu can be used for synthesis of PROTAC BRD4 Degrader-14 (HY-138637).
  • HY-181759
    CBP/p300/BRD4 ligand-1
    		Ligand
    CBP/p300/BRD4 ligand-1 is a small-molecule inhibitor targeting CBP, p300, and BRD4. CBP/p300/BRD4 ligand-1 competitively binds to the functional domains of target proteins without disrupting key interactions. CBP/p300/BRD4 ligand-1 can be used for the construction of dual-target PROTAC degraders (HY-181758) in studies related to prostate cancer and other cancers.
  • HY-176467
    TAF1 ligand 1
    		Ligand
    TAF1 ligand 1 is a TAF1 ligand. TAF1 ligand 1 can be used as a Ligands for Target Protein for PROTAC synthesis, such as ZS3-046 (HY-176457).
  • HY-175679
    BRD2 BD1 ligand-1
    		Ligand
    BRD2 BD1 ligand-1 is a potent BRD2 BD1 ligand (Ligands for Target Protein for PROTACs) can be used in the synthesis of PROTAC BRD2 BD1 Degrader-1 (HY-175678).
  • HY-175611
    FLT3/JAK2/BRD4 ligand-1
    		Ligand
    FLT3/JAK2/BRD4 ligand-1 is a FLT3/JAK2/BRD4 ligand. FLT3/JAK2/BRD4 ligand-1 can be used for synthesis PROTAC FLT3/JAK2/BRD4 Degrader-1(HY-175610).
  • HY-182371
    BRD4 ligand 15
    		Ligand
    BRD4 ligand 15 (compound 5) is a BRD4 ligand and alkyne-modified chalcone derivative, which serves as a building block for the synthesis of BRD4-targeting PROTAC TKP-5 (HY-182370).
  • HY-P11462
    UNO peptide
    		Ligand
    UNO peptide is a MRC1-expressing TAMs (MEMs)-targeting peptide. UNO peptide targets CD206 on MEMs across a spectrum of solid tumors. UNO peptide can be used in the research of MEMs in breast cancer.
  • HY-132942
    PROTAC BRD4 ligand-2
    		Ligand
    PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
  • HY-182084
    BRD9 ligand-12
    		Ligand
    BRD9 ligand-12 is a BRD9 ligand. BRD9 ligand-12 can be used as a ligand for target protein for PROTAC to develop and design degradative agents for PROTAC BRD9, such as XYD270 (HY-182082). XYD270 inhibits tumor growth in a mouse model of acute myeloid leukemia. XYD270 can be used in research related to synovial sarcoma and acute myeloid leukemia.
  • HY-181950
    BRD9 ligand-10
    		Ligand
    BRD9 ligand-10 is a ligand targeting BRD9. BRD9 ligand-10 can be used as a target protein ligand for the synthesis of PROTAC BRD9 Degrader-10 (HY-181949).